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It is used to treat gastroesophageal reflux disease (GERD), ulcers, certain bacteria in the stomach, and inflammation of the esophagus. You may be prescribed generic Nexium for Zollinger-Ellison syndrome and gastroesophageal reflux disease, as well as to relieve and promote healing of the esophagus damaged by excessive amounts of stomach acid WHY NEXIUM? Do not take Nexium if you have a history of allergic reactions to …. Nexium Safety Guide: Contraindications, Recommendations for Use, Precautions. This proton pump inhibitor can be taken for a few days or weeks, and the directions of a medical professional should be followed. Antifungal drugs, diuretics, and protease inhibitors can lead to devastating results if Nexium interacts with them Jan 09, 2012 · Worse, Nexium is mentioned by name, multiple times, and Nexium is actually a drug which should never have even been approved by the FDA. There are other branded PPIs available and only some of them have generic equivalents. 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